Imininingwane enzuzo
Indlela yokuthumela:Ikhuriya
Ukubonisa umlingani
Impahla Yamakhemikhali:
| Igama | 2,4-Difluorobenzylamine |
| Amagama Afanayo | RARECHEM AL BW 0282 2,4-Fluorobenzylamine 2,4-DIFLUOROBENZYLAMINE 2,4-Difluorobenzylamine 2,4-Difluorobenzyl Amine 2,4-Difluorobenzenemethanamine (2,4-Difluorophenyl)methanamine Benzenemethanamine, 2,4-difluoro- 1-(2,4-difluorophenyl)methanamine (2,4-difluorophenyl)methanaminium 2,4-DIFLUOROBENZYLAMINE HYDROCHLORIDE |
| CAS | 72235-52-0 |
| EINECS | 276-502-0 |
| InChI | InChI=1/C7H7F2N/c8-6-2-1-5(4-10)7(9)3-6/h1-3H,4,10H2/p+1 |
| InChIKey | QDZZDVQGBKTLHV-UHFFFAOYSA-N |
72235-52-0 - Izakhiwo Ze-Physico-chemical
| Ifomula Yamangqamuzana | C7H7F2N |
| Isisindo Se-Molar | 143.13 |
| Ukuminyana | 1.204 g/mL ku-25 °C (lit.) |
| Iphoyinti lokuncibilika | 255-256 °C(Solv: i-N,N-dimethylformamide (68-12-2)) |
| Iphuzu Lokubila | 82-84 °C (15 mmHg) |
| Iphuzu Lokushisa Okuvutha | 155°F |
| Ingcindezi Yomhwamuko | 1.02mmHg ku-25°C |
| Ukubukeka | Ukwetshezi |
| Isisindo Esithile | 1.204 |
| Umbala | Kucacile kungenawo umbala kuya kokuphuzi okukhanyayo |
| BRN | 3539259 |
| pKa | 8.58±0.10(Kubikezelwe) |
| Isimo Sokugcina | ngaphansi kwegesi engasebenzi (i-nitrogen noma i-Argon) ku-2–8 °C |
| Kuzwela | Izwa umoya |
| Inkomba Yokukhanya | n20/D 1.49(lit.) |
72235-52-0 - Ingozi Nokuphepha
| Izimpawu Zengozi | C – Eyokugqwala Ukulanda isithombe sangaphandle kwehlulekile. Ukuze umamukeli abone lesi sithombe, sicela usisuse lesi sithombe, bese usilanda endaweni yakho, bese usinamathisela ku-imeyili. https://res.chembk.com/assets/images/hs/C.gif Susa |
| Amakhodi Engozi | 34 – Kubangela ukushiswa |
| Incazelo Yokuphepha | S26 – Uma kuthinteka emehlweni, geza ngokushesha ngamanzi amaningi bese uthola izeluleko zokwelashwa. S27 – Khumula ngokushesha zonke izingubo ezingcolile. S36/37/39 – Gqoka izingubo zokuzivikela ezifanele, amagilavu kanye nokuvikela amehlo/ubuso. S45 – Uma kwenzeka ingozi noma uma uzizwa ungaphathekile kahle, thola izeluleko zokwelashwa ngokushesha (khombisa ilebula uma kungenzeka.) S25 – Gwema ukuthintana namehlo. |
| Ama-UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| Ikhodi ye-HS | 29214990 |
| Inothi Lengozi | Kuyagqwala |
| Ikilasi Lengozi | 8 |
| Iqembu Lokupakisha | III |
| Umkhakha Wokusetshenziswa | Ukusetshenziswa Okubalulekile |
|---|---|
| Imithi (I-API Synthesis) | Isakhi esiyisisekelo sokwakha imishanguzo elwa namagciwane (isb., i-HIV protease inhibitors, i-HCV NS3/4A inhibitors), imishanguzo elwa nomdlavuza (i-kinase inhibitors, i-PARP inhibitors), kanye nemishanguzo ye-CNS. Ingxenye ye-difluorobenzylamine itholakala kumamolekyuli afana ne-fluvoxamine (i-SSRI antidepressant), i-voriconazole (i-antifungal), kanye nezinye izinhlanganisela ezicwaningwayo. |
| Amakhemikhali Ezolimo | Isetshenziswa ekwakhiweni kwezibulala-zinambuzane zesimanje ezine-fluorine, kufaka phakathi izibulala-fungus (isb., ama-fluopyram analogs), izibulala-khula, nezibulala-zinambuzane. Ukufakwa kwe-fluorine kuthuthukisa ukuzinza kwemvelo nokukhethwa kwelitshe. |
| I-Peptide/Peptidomimetic Chemistry | Isebenza njengesandulela sezinto ezisuselwa ku-fluorinated benzylamine ezisetshenziswa ekuguqulweni kwe-peptide kanye nezixhumi ze-PROTAC (proteolysis-targeting chimera). |
| Ukwenziwa Kwamakhemikhali Acwengekile | Isixazululo sokukhiqiza ama-amine akhethekile, ama-amide, ama-Schiff bases, kanye nezinhlanganisela ze-heterocyclic (isb., i-benzimidazoles, i-quinazolines) ezinomsebenzi wokwelapha othuthukisiwe. |
| Isayensi Yezinto | Isetshenziswa ekukhiqizeni ama-polymer ane-fluorine, izibonisi ze-crystal liquid (LCDs), kanye nezingubo ezisebenzayo ezidinga izici zikagesi eziyingqayizivele. |
I-Xinchem ingumkhiqizi ohamba phambili we-2,4-difluorobenzylamine onolwazi olujulile lwekhemistri ye-fluorination kanye namakhono aqinile e-CDMO:
| Ipharamitha | Ikhono |
|---|---|
| Umthamo Wokukhiqiza Wonyaka | 200+ amathani amametric (ayandiseka) |
| Izinga Lokuhlanzeka | Izinga lemithi (≥99.0% GC), Izinga locwaningo (≥98.0%), Ukuhlanzeka okwezifiso (kuze kufike ku-99.9%) |
| Ukwenziwa Ngokwezifiso | Amaphethini okufaka esikhundleni enzelwe (mono-, di-, trifluorinated benzylamines), ama-analog anelebula isotopically (²H, ¹³C, ¹⁵N), ukwenziwa kwe-derivative (ama-amide, ama-carbamate, ama-sulfonamide, ama-urea, ama-Schiff base) |
| Ukuthuthukiswa Kwenqubo | Ukuthuthukiswa komzila wokwenyusa izinga ngendlela engabizi; ukufakwa kwe-fluorine okugeleza okungapheli kuyatholakala |
| Izinketho Zokupakisha | 1 kg, 5 kg, 25 kg idramu, 50 kg idramu ye-HDPE, 200 kg idramu yensimbi, ukupakisha okwezifiso |
| MOQ (Inqwaba/Ukudayisela ngobuningi) | 100 g (amasampula e-R&D); 100 kg (ama-oda amakhulu) |
| Isikhathi Sokuhola | 3–5 izinsuku kusitoko; 14–21 izinsuku ekwenziweni ngokwezifiso |
| Izimakethe Zokuthumela Ngaphandle | I-USA, i-EU (iJalimane, iSwitzerland, i-UK, iFrance), iJapan, iSouth Korea, iRussia, i-India |
| Ezokuthutha | Ukuthunyelwa kwemvelo noma okufrijiwe; ukuphathwa ngokomsebenzi kwezinto ezibolayo (Ikilasi 8) |
