Isingeniso

I-Methyl 2-[[(2,4-dimethyl-3-cyclohexene-1-yl)methylene]amino]benzoate, eyaziwa nangokuthi i-MDA-MB-231 (ICH3 methamphetamine), iyinhlanganisela yemvelo.

Ikhwalithi:

- Ukubukeka: uketshezi olunamafutha olungenambala kuya kokuphuzi okukhanyayo;

- Ukuncibilika: iyancibilika kuma-organic solvents afana notshwala, ama-ether nama-ester, ayincibiliki emanzini;

- Iphunga: Linomphunga okhethekileyo ocindezelayo.

Ukusetshenziswa:

- Ukuhlanganiswa kwamakhemikhali: Ingasetshenziselwa i-aminomethylation ekuhlanganiseni kwamakhemikhali emizimbeni ephilayo.

Indlela:

I-MDA-MB-231 yalungiselelwa ngokusabela kwezinhlanganisela ze-benzyl nezinhlanganisela ze-methylene. Indlela yokulungiselela eqondile ihlanganisa indlela yokuhlanganisa izinyathelo eziningi, okuhlanganisa ukuhlanganiswa kwama-cyclohexene rings, ukuhlanganiswa kwe-cyclohexetoketone, kanye nokusabela ne-methyleneamine.

Ulwazi Lokuphepha:

- I-MDA-MB-231 ingase ibe nemiphumela ecasulayo neyokulimaza kubantu nasemvelweni lapho ichayeka noma idliwa, futhi kufanele isetshenziswe ngokuqapha;

- Gwema ukuhogela umusi noma intuthu evela kule nhlanganisela futhi uqinisekise ukuthi isetshenziswa endaweni enomoya ohamba kahle;

- Lapho igcinwa, gwema ukuthintana nama-oxidants, gcina endaweni epholile, eyomile, enomoya ohamba kahle, kude nomlilo namazinga okushisa aphezulu.